Electroconvulsive shock induced amnesia and recovery

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BR-16A restricts development of electroconvulsive shock-induced retrograde amnesia.

Forty nine adult male Sprague Dawley rats were selected for rapid learning in a T-maze to study the effects of BR-16A, a herbal preparation on ECS-induced retrograde amnesia. Half the rats received 200 mg/kg BR-16A and the other half received vehicle alone. The rats were trained to run into the enclosed chamber of either the left or the right arm on a T-maze; a food pellet served as a reward in...

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Pre-electroconvulsive shock administration of calcium channel blockers reduces retrograde amnesia induced by ECS.

Effect of pre-electroconvulsive shock (ECS) administration of calcium channel blockers (CCBs) like verapamil, diltiazem, nifedipine, nimodipine, flunarizine and cinnarizine on retrograde amnesia induced by ECS was examined using passive avoidance paradigm in rats. The groups (Gr 1-7) of adult, male Wistar rats received true ECS with CCBs (5mg/kg; i.p) or vehicle (10 ml/kg; ip) and other groups ...

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Single Electroconvulsive Shock and Dopamine Autoreceptors

Dopamine (DA) auto receptor down regulation has been suggested to mediate the therapeutic effect of antidepressant treatments including electroconvulsive therapy (ECT). Suggestion has also been made that a single ECT may have antidepressant potential via such a mechanism. The present study was therefore conducted to assess the effects ill a single electroconvulsive shock (ECS) on dopamine auto ...

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Retrograde amnesia after electroconvulsive therapy: a temporary effect?

OBJECTIVE Although electroconvulsive therapy (ECT) is generally considered effective against depression, it remains controversial because of its association with retrograde memory loss. Here, we assessed memory after ECT in circumstances most likely to yield strong retrograde amnesia. METHOD A cohort of patients undergoing ECT for major depression was tested before and after ECT, and again at...

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Electroconvulsive Therapy in Severe Depression: Is Amnesia a Problem?

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ژورنال

عنوان ژورنال: Psychonomic Science

سال: 1968

ISSN: 0033-3131

DOI: 10.3758/bf03331383